CHE552

Synthetic Organic Chemistry
Year / Semester: 
2nd Year

BLOCK I: ORGANIC SYNTHESIS-I                                                                          
Unit –1:     A brief review of functionalisation and functional group transformation reactions and oxidation of alkanes and alkenes                                                              
Unit – 2:   Oxidation of alcohols                                                                                          
Unit – 3:   Reduction by catalytic hydrogenations                                                              
Unit – 4:   Reduction by hydride transfer agents                                                                 
Unit – 5 :   Reductions by dissolving metals.                                                                                     

BLOCK II :ORGANIC SYNTHESIS – II                                                                      
Unit – 6:    Formation of carbon-carbon single bond
Unit – 7:    Formation of carbon-carbon double bond                                                         
Unit – 8:    Synthetic applications of organoboranes                                                           
Unit – 9:    Synthetic applications of organosilanes                                                             
Unit – 10:  Protecting groups in organic synthesis                                                               

BLOCK III : SYNTHETIC STRATEGIES
Unit – 11 :   Introduction, target selection and terminology                                                
Unit – 12 :   Disconnection approach with examples                                                           
Unit – 13 :   Strategic bond in carbocyclic and heterocyclicsystems
Unit – 14 :   Applications of some important strategies in organic synthesis                       
Unit – 15 :   Some selected synthesis                                                                                   

BLOCK IV : ASYMETRIC SYNTHESIS                                                                     
Unit – 16 :    Topicity, configurational descritors and stereoselectivity                               
Unit – 17 :    Principles of asymmetric synthesis and analysis of stereoisomer mixtures     
Unit – 18 :    Substrate controlled methods                                                                         
Unit – 19 :    Auxilliary controlled methods                                                                        

Unit – 20 :    Reagent controlled and catalyst controlled synthesis