CHE554

Drugs and Pharmaceuticals
Year / Semester: 
2nd Year

BLOCK 1 : DRUG DISCOVERY, DESIGN AND DEVELOPMENT               
Unit – 1 : Drug discovery, design and development                                                    
Unit – 2 : Concepts of receptors, agonists and antagonists                                          
Unit – 3 : Drug development of Salbutamol, cimetidine and captopril                        
Unit – 4 : Structure activity relationship studies – I                                                     
Unit – 5 : SAR studies – II Development of oxaminiquine & SAR studies of Sulphonamides and benzepines                                                                  

BLOCK 2 : DRUGS ACTING ON DIFFERENT TARGETS – I                       
Unit – 6 : Combinatorial synthesis                                                                                
Unit – 7 : Quantitative structure activity relationships – (QSAR)                               
Unit – 8 : Pharmacokinetics, prodrugs and clinical trials
Unit – 9 : Drugs acting on metabolic process
Unit – 10 : Drugs acting on cell walls and cell membranes

BLOCK 3 : DRUGS ACTING ON DIFFERENT TARGETS – II                      
Unit – 11 : Drugs acting on the nervous system                                                           
Unit – 12 : enzyme inhibitors                                                                                        
Unit – 13 : Drugs effecting cholinergic nervous system                                               
Unit – 14 : Drugs acting on histamine receptors and ion channels                               
Unit – 15 : Drugs acting on genetic material                                                                

BLOCK 4 : MANUFACTURE AND ANALYSIS OF DRUGS                           
Unit – 16 : Introduction to chiral drugs                                                                        
Unit – 17 : Synthesis of chiral drugs
Unit – 18 : Drugs and drug intermediate from fermentation                                       
Unit – 19 : Drug analysis                                                                                              
Unit – 20 : Quality control methods in drug manufacturing and formulations

BLOCK 1 : DRUG DISCOVERY, DESIGN AND DEVELOPMENT
This block deals with drug discovery, design and development; it is divided into five units:
Unit – 1 : Drug discovery, design and development
Unit – 2 : Concepts of receptors, agonists and antagonists
Unit – 3 : Drug development of Salbutamol, cimetidine and captopril
Unit – 4 : Structure activity relationship studies – I
Unit – 5 : SAR studies – II Development of oxainiquine & SAR studies of sulphonamides  benzodiazepines